Is it possible to run 1 program like wine or blender through a server with 1 master node and 4 nodes

I would like to run a program across multiple devices on an ubuntu server, I’m going to use 1 desktop for the master node and 4 laptops for nodes.

Are you wanting to basically set up a “remote apps” kind of setup? The best way that I’m aware of is to use X2Go and use the remote apps feature.